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    1. Home
    2. Biotech Solutions
    3. Development of Small and Large Molecules

    Development of Small and Large Molecules

    Biology and medicine need to combine their resources to discover additional natural regulatory mechanisms of molecular and body processes in order to contribute to the maintenance of body metabolism and physiological functions.

    Overview
    1. Synthesis of Small Molecules
    2. Synthesis of Large Molecules
    3. Purification of Molecules
    4. Analysis of Molecules
    5. Equipment and Safety

    Small molecules (e.g. drugs) have been explored as substitutive organic compounds that are now instrumental in impacting cellular players, and have become beneficial effectors against known body disorders.

    Large molecules have a complex structure that can affect biologic functions and influence body mechanisms, thereby becoming essential therapeutic media and future medical treatments.

    The development of small and large molecules is dependent on highly regulated technological processes right up to the bio-convenient manufacturing stage. Many major biotech providers seek to deliver further therapeutic tools and solutions for known human illnesses, or in many cases for life-influencing conditions in dermal, cardiovascular or neural diseases.

    1. Synthesis of Small Molecules


    Small molecules are synthesized via synthetic methods from simpler organic precursors that contain a variety of functional groups. Through the Fisher Scientific channel you can choose from a variety of organic, organometallic or heteroatom-functionalized compounds (e.g. organic oxygen compounds, such as organic acids and their derivatives).

    Top Categories

    Hydrocarbons

    Hydrocarbons

    Organometallic Compounds

    Organometallic Compounds

    Organic Oxygen Compounds

    Organic Oxygen Compounds

    Organic Nitrogen Compounds

    Organic Nitrogen Compounds

    Organic Acids and Derivatives

    Organic Acids and Derivatives

    Standards

    Standards

    Resources

    Chemicals Essentials Handbook

    Filename
    15488_Chemical_Essentials_Handbook.pdf
    Size
    8 MB
    Format
    application/pdf

    Overview of Buffers for Life Science

    Filename
    Overview_of buffers_for_the_life_science_research.pdf
    Size
    14 MB
    Format
    application/pdf

    2. Synthesis of Large Molecules


    Synthesis of large molecules (e.g. peptides) requires different consumables, ranging from an affordable source of amino acids to commonly used reagents (e.g. acetic anhydride) as well as solid-phase substrates required to obtain ready-to-use peptide polymers.

    Top Categories

    Amino Acids

    Amino Acids

    Peptides

    Peptides

    Buffers and Solutions

    Buffers and Solutions

    Polyamides

    Polyamides

    Polyethylene Glycols

    Polyethylene Glycols

    Water

    Water

    Resources

    Overview of Chemicals for Chromatography

    Filename
    15488_Chemicals_Chromatography_EN.pdf
    Size
    1 MB
    Format
    application/pdf

    3. Purification of Molecules


    Purification by chromatography permits accurate compositional analysis that is useful in pre-clinical or analytical research workflows. The Fisher Scientific channel can offer a wide range of products for analysis, from columns and cartridges to protein digestion and purification tools, as well as mass spectrometry reagents and solvents.

    Top Categories

    Columns and Cartridges

    Columns and Cartridges

    Ion Exchange Columns

    Ion Exchange Columns

    Protein Purification

    Protein Purification

    Solvents

    Solvents

    Protein Digestion

    Protein Digestion

    Mass Spectrometry Reagents

    Mass Spectrometry Reagents

    Resources

    Overview of Preparative LC Columns

    Filename
    15488_ccs_preparative_hplc_columns.pdf
    Size
    711 KB
    Format
    application/pdf

    Overview of Syringe Filters

    Filename
    15488_Acrodisc_one_technical_guide.pdf
    Size
    4 MB
    Format
    application/pdf

    4. Analysis of Molecules


    For analysis of both small and large molecules, a variety of devices and reagents are required, including HPLC, UHPLC, FPLC, and LC-MS systems. The Fisher Scientific channel can offer a variety of column types, as well as high-quality solvents, buffers, standards, and other accessories suitable for all your analytical needs.

    Top Categories

    Acetonitrile

    Acetonitrile

    Methanol

    Methanol

    Solid Phase Extraction

    Solid Phase Extraction

    HPLC Columns

    HPLC Columns

    Gel Filtration Media and Columns

    Gel Filtration Media and Columns

    Standards

    Standards

    Resources

    Overview of Centrifugal Devices

    Filename
    15488_CentrifugalDevice_SS.pdf
    Size
    3 MB
    Format
    application/pdf

    5. Equipment and Safety


    A clean and safe work environment is essential for the synthesis and manufacture of high-demand molecules and polymers. The Fisher Scientific channel can offer a wide variety of personal protective equipment (PPE) and safety clothing, as well as other products required to maintain your work space in regard to clinical or other quality regulations.

    Top Categories

    Chemical Monitoring Instrumentation

    Chemical Monitoring Instrumentation

    Controlled Environment

    Controlled Environment

    Coveralls, Lab Coats and Accessories

    Coverall, Lab Coats and Accessories

    Facility Maintenance and Safety

    Facility Maintenance and Safety

    First Aid and Medical

    First Aid and Medical

    Personal Protective Equipment

    Personal Protective Equipment

    Resources

    Overview of Safety Products

    Filename
    15488_Safety_Brochure_EN.pdf
    Size
    8 MB
    Format
    application/pdf

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    Fisher Scientific - part of Thermo Fisher Scientific

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