accessibility menu, dialog, popup

UserName

Discover Our Special Offers

Save Now

Fisher Scientific Logo
  • flag icon for Portugal
Search
    • Order Status
    • Quick Order
    • Support
    • Sign In
      chevron-down
      • Shopping Tools
      • My Lists
      • Quick Order
      • Chemical Search
      • Order Oligo's
      • Orders
      • Order Status
      • Account
      • Account Dashboard
      • My Profile
      • Password & Security
      • Create Web Profile
      • Register for an Account

    • Sign In
  • View Shopping Cart
    chevron-down
  • Fisher Scientific Logo Fisher Scientific Logo
    Sign In
    Don't have an account?  Create an Account
    Account
    Main Menu
    Account
    Account Dashboard
    My Profile
    Shipping & Billing Addresses
    Add New Delivery Address
    Password and Security
    Create Web Profile
    Register for an Account
    Orders
    Main Menu
    Orders
    Order Status
    Quotes
    Invoices
    Returns
    Multi-Tier requisitions
    Shopping Tools
    Main Menu
    Shopping Tools
    My Lists
    Quick Order
    Chemical Search
    Search Third Party Products
    Request for Non-Catalogue Product
    Order Non-Catalogue Products
    Order Oligo Products / TaqMan® Assays
    Products
    Antibodies
    Products
    Antibodies
    Antibody Panels and Kits
    Antibody Production and Purification Reagents and Kits
    Bovine Secondary Antibodies
    Donkey Secondary Antibodies
    Goat Secondary Antibodies
    Buffers and Standards
    Primary Antibodies for ELISA
    Primary Antibodies for Immunohistochemistry
    Primary Antibodies for Western Blotting
    Secondary Antibodies
    Antibodies Advanced Search
    Shop All Antibodies
    Chemicals
    Products
    Chemicals
    Acids
    Bases
    Biochemical Reagents
    Buffers and Standards
    Organic Compounds
    Organometallic Compounds
    Salts and Inorganics
    Solvents
    Water
    Search by Chemical Structure
    Shop All Chemicals
    Lab Consumables
    Products
    Lab Consumables
    Beakers and Lids
    Bottles, Jars, and Jugs
    Dishes
    Dispensers
    Filters and Filtration
    Flasks
    Microplates
    Pipettes
    Tubes
    Vials
    Shop All Lab Consumables
    Lab Equipment and Instruments
    Products
    Lab Equipment and Instruments
    Balances and Scales
    Centrifuges
    Cold Storage Products
    Fume Hoods
    Hotplates and Stirrers
    Incubators
    Microscopes
    pH and Electrochemistry
    Pumps and Tubing
    Shakers
    Shop All Lab Equipment and Instruments
    Lab Furniture and Storage
    Products
    Lab Furniture and Storage
    Desks and Tables
    Fume Hoods
    Laboratory Benches and Tables
    Laboratory Carts and Accessories
    Safety Cabinets
    Seating
    Shelving
    Sinks and Drains
    Storage Cabinets
    Task Lighting
    Shop All Lab Furniture and Storage
    Life Sciences Products
    Products
    Life Sciences Products
    Antibodies
    Biochemical Reagents
    Cell Analysis Products
    Cell Culture Media
    Cellular Imaging
    Gel Electrophoresis Equipment and Supplies
    Life Sciences Buffers
    Molecular Biology Reagents and Kits
    PCR Equipment and Supplies
    Protein Analysis Reagents
    Recombinant Proteins
    Shop All Life Sciences Products
    Safety Products
    Products
    Safety Products
    Chemical Detection
    Cleaners and Disinfectants
    Eye and Face Protection
    Fall Protection and Confined Space Entry
    Hand Protection
    Lockout Tagout Products
    Radiation Monitoring Instrumentation
    Respiratory Protection
    Safety Clothing
    Signs and Tags
    Spill Control and Containment
    Wipes and Wipe Accessories
    Shop All Safety Products
    Shop All Products
    Browse Featured Brands
    Tools
    Search by Chemical Structure
    Chem dex Chemical Search
    Custom Assays, Antibodies, Oligos
    Applications
    Cell Biology
    Applications
    Cell Biology
    Cell Culture and Modification
    Cell Analysis
    Chemistry
    Applications
    Chemistry
    Analytical Testing Methods
    Organic Synthesis
    Chromatography
    Genomics
    Applications
    Genomics
    Molecular Biology Methods
    PCR and qPCR
    Microbiology
    Production & Bioprocessing
    Applications
    Production & Bioprocessing
    Cell & Gene Therapy
    Proteomics
    Applications
    Proteomics
    Protein Biology Methods
    Safety
    Applications
    Safety
    Contamination Control and Controlled Environments
    Browse All Applications
    Business Solutions
    Biopharma
    Biotech
    Green Solutions
    Food and Beverage
    Testing Lab and Environmental
    Chemical and Cosmetic
    Clean Energy and Battery
    Programs and Services
    Edge Program
    Encompass Procurement Services
    Every Space
    New Lab Start-Up Program
    News Corner
    SureTRACE Program
    Sustainability Program
    Services
    Programs and Services
    Services
    Scan2Order
    SureTRACE+Program
    Unity Lab Services
    Browse All Programs
    Documents and Certificates
    Main Menu
    Documents and Certificates
    Certificates
    Safety Data Sheets
    SureTRACE
    Special Offers
    Main Menu
    Special Offers
    Promo Image - Spotlight
    Spotlight
    Save with our Spotlight Offers throughout the year on a variety of products and categories.
    Promo Image - Product of the month
    Product of the month
    Discover Fisherbrand's Product of the Month and upgrade your lab now.
    Promo Image - Outlet Corner
    Outlet Corner
    Take advantage of exceptional discounts on unsold products.
    View All Special Offers
    Help and Support
    How to order
    Order History
    My Lists
    Request a Quote
    Business Account
    Chemical Structure Search
    Finding Safety Data Sheets
    Finding Product Certificates
    Account Creation
    Help & Support Center
    Register for a Business Account My Lists Quick Order
    1. Home
    2. Biotech Solutions
    3. Immunotherapies
    4. Innovative mAbs Solutions

    Innovative mAbs Solutions

    Tackle mAbs development challenges with robust, cost-effective solutions.

    1. Discovery and Development
    2. Optimization and Scale Up
    3. Clarification and Purification
    4. Protein Characterization and Analysis
    5. Fill and Finish
    6. Single-Use Solutions

    1. Discovery and Development


    mAbs discovery and development necessitate a series of intricate procedures aimed at achieving consistent and reproducible outcomes. Employing a Chinese Hamster Ovary (CHO) platform enables efficient and straightforward selection and scale-up of clones for manufacturing. Explore our range of cell line development kits, optimized media, supplements, feeds, essential equipment, and other tools that expedite the process and minimize development time.

     

    Top Products

    Gibcoâ„¢ CD CHO Medium

    Optimized for the growth of CHO cells and expression of recombinant proteins in suspension culture

    Gibcoâ„¢ CD CHO Medium

    DWK Life Sciences Wheatonâ„¢ CELLineâ„¢ Bioreactor Flask

    Optimized small scale mAbs production

    DWK Life Sciences Wheatonâ„¢ CELLineâ„¢ Bioreactor Flask

    BINDERâ„¢ Series CB - COâ‚‚ Incubator, with Hot Air Sterilization and Heat Sterilizable COâ‚‚ Sensor

    Fast and 100% protected cell and tissue cultivation

    BINDERâ„¢ Series CB - CO2 Incubator, with Hot Air Sterilization and Heat Sterilizable CO2 Sensor

    Eppendorf Centrifuge 5427 R (EU-IVD)

    With a natural refrigerant R290 that protects your samples and the planet

    Eppendorf Centrifuge 5427 R (EU-IVD)

    Featured Products

    Unable to load product results.

    Unable to load product results.

    Please try again later.

    Essential Categories

    View All COâ‚‚ Incubators
    View All CHO Media
    View All Cell Culture Flasks

    2. Optimization and Scale Up


    Efficient conversion from pilot to process scale and smooth technology transfer demand meticulous organization, effective communication, and thorough documentation. Choose appropriate media, single-use products, and instruments that adhere to stringent quality standards, ensuring high performance, scalability, enhanced speed, flexibility, and reduced capital requirements.

     

    Top Products

    Eppendorfâ„¢ New Brunswickâ„¢ S41i COâ‚‚ Incubator Shaker

    Discover the environmentally friendly CO₂ incubation shaker with 120°C disinfection, designed for hybridoma cultures and antibody expression

    Eppendorfâ„¢ New Brunswickâ„¢ S41i CO2 Incubator Shaker

    Gibcoâ„¢ ExpiCHOâ„¢ Stable Production Medium

    Specifically designed to simplify your cell line development process into production with minimal effort

    Gibcoâ„¢ ExpiCHOâ„¢ Stable Production Medium

    Wheatonâ„¢ D Model R2P 2.0 Roller Culture Apparatus

    Enables effective roller bottle cell culture

    Wheatonâ„¢ D Model R2P 2.0 Roller Culture Apparatus

    Corningâ„¢ HYPERFlaskâ„¢ M Cell Culture Vessels

    Designed specifically for manual use, high-yield and high-performance

    Corningâ„¢ HYPERFlaskâ„¢ M Cell Culture Vessels

    Featured Products

    Placeholder

    Catalog Number 10045411

    Corningâ„¢ Polycarbonate Erlenmeyer Flasks
    Placeholder

    Catalog Number 6259022

    Thermo Scientificâ„¢ CO2 Resistant Shakers
    Viewing 0-2 of 2

    Essential Categories

    View All Roller Bottles
    View All Orbital Shakers
    View All Floor Model Centrifuges

    3. Clarification and Purification


    Optimizing the downstream steps in monoclonal antibody (mAb) processing is paramount for guaranteeing product quality, yield, and sterility. Explore our comprehensive range of products designed to enhance separation efficiency and filtrate quality, all while minimizing biomanufacturing costs.

    Top Products

    Thermo Scientificâ„¢ MabCaptureCâ„¢ High Capacity Protein A Resin

    High-performance chromatography resin for capturing monoclonal antibodies (mAbs) and recombinant Fc-tagged fusion proteins

    Thermo Scientificâ„¢ MabCaptureCâ„¢ High Capacity Protein A Resin

    Cytiva MabSelect PrismA Chromatography Resin

    With enhanced alkaline stability and binding capacity for improved process economy in antibody purification

    Cytiva MabSelect PrismA Chromatography Resin

    Thermo Scientificâ„¢ SpeedVacâ„¢ SRF110 Refrigerated Centrifugal Vacuum Concentrator and Rotors

    State of the art centrifugation, vacuum, and heat technologies for removing solvents and concentrating heat sensitive biological samples

    Thermo Scientificâ„¢ SpeedVacâ„¢ SRF110 Refrigerated Centrifugal Vacuum Concentrator and Rotors

    Merck Ultrafiltration Discs, 30 kDa NMW, Ultracelâ„¢ Regenerated Cellulose

    Achieve high yields of mAb without any compromise in the final quality or high concentration 

    Merck Ultrafiltration Discs, 30 kDa NMW, Ultracelâ„¢ Regenerated Cellulose

    Featured Products

    Placeholder

    Catalog Number 8555008

    Cytiva HiTrap MabSelect PrismA Column
    Placeholder

    Catalog Number 7250485

    Cytivaâ„¢ HiTrapâ„¢ Chromatography Columns with MabSelectâ„¢ VL Protein L Resin
    Placeholder

    Catalog Number 15893965

    Cytiva HiScreen MabSelect PrismA Column
    Viewing 1-3 of 3

    Essential Categories

    View All Protein Purification Reagents and Kits
    View All Ultrafiltration Filters and Devices
    View All Protein Resins

    4. Protein Characterization and Analysis


    Achieving optimal monoclonal antibody (mAb) production requires efficient protein characterization and analysis. Explore our advanced solutions for precise protein identification, quantification, structural analysis, post-translational modification profiling, and stability assessment.

    Top Products

    Applied Biosystemsâ„¢ QuantStudioâ„¢ Absolute Q Package, including Digital PCR System, desktop PC, Smart Start Training and 1 Year Extended Warranty

    Quantifies low frequency gene targets with higher accuracy and without the need for a standard curve

    Applied Biosystemsâ„¢ QuantStudioâ„¢ Absolute Q Package, including Digital PCR System, desktop PC, Smart Start training and 1 Year extended warranty

    Implenâ„¢ NanoPhotometerâ„¢ N120 Multichannel Micro-Volume UV-VIS Spectrophotometer

    High-throughput measurements of up to 12 samples without consumables with contamination assessment

    Implenâ„¢ NanoPhotometerâ„¢ N120 Multichannel Micro-Volume UV-VIS Spectrophotometer

    Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC Columns

    Ideal for charge variant analysis and recommended for use with mAbs and therapeutic proteins

    Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC Columns

    Thermo Scientific™ MAbPac™ SCX-10 RS Monoclonal Antibody Analysis Column, 5μm

    Ideal for characterization and quality control assessment of mAbs

    Thermo Scientific™ MAbPac™ SCX-10 RS Monoclonal Antibody Analysis Column, 5μm

    Featured Products

    Placeholder

    Catalog Number 6340237

    Thermo Scientificâ„¢ Varioskanâ„¢ LUX Multimode Microplate Reader
    Viewing -1-1 of 1

    Essential Categories

    View All Isotyping and Characterization Products
    View All UV-Vis Spectrophotometers
    View All HPLC Columns

    5. Fill and Finish


    To meet the requirements of fill and finish processes for mAb production, products must be prepared in an ISO Class 5 environment and comply with sterile, pyrogen-free, and particulate-free standards (USP71, USP85, USP758). Additionally, they should be validated for storage of frozen or lyophilized drug product and compatibility with the protein and excipients in the final formulation. Explore our product choices for mAb fill and finish, including RTF vials, chemicals, buffers, production water, and environmental control products.

    Top Products

    Stevanato Group EZ-fillâ„¢ Vials from DWK Life Sciencesâ„¢

    Ready to use sterile vials for aseptic filling

    Stevanato Group EZ-fillâ„¢ Vials from DWK Life Sciencesâ„¢

    Masterflexâ„¢ B/Tâ„¢ MasterSenseâ„¢ BioPharma Pumps

    High-flow pump for process applications with an intuitive touch-screen interface and advanced connectivity

    Masterflexâ„¢ B/Tâ„¢ MasterSenseâ„¢ BioPharma Pumps

    DWK Life Sciences DURANâ„¢ PURE Bottle, Amber, with DIN Thread

    Protection of light sensitive active ingredients

    DWK Life Sciences DURANâ„¢ PURE Bottle, Amber, with DIN Thread

    DWK Life Sciences DURANâ„¢ PURE Premium Screw Cap

    Pharma grade closures for Type 1 glass bottles

    DWK Life Sciences DURANâ„¢ PURE Premium Screw Cap

    Featured Products

    Placeholder

    Catalog Number 10410911

    Thermo Scientific Acros Polysorbate 80
    Placeholder

    Catalog Number 17811391

    MP Biomedicals Sodium dodecyl sulfate, 99.5%, MP Biomedicalsâ„¢
    Viewing 0-2 of 2

    Essential Categories

    View All Sample Vials
    View All Round Glass Bottles
    View All Surfactants

    6. Single-Use Solutions


    Our innovative single-use technologies accelerate biological manufacturing, enhancing flexibility and efficiency in upstream and downstream workflows. Achieve consistent and scalable processes with our industry-leading standard single-use products.

     

    Top Products

    Corningâ„¢ CELLine Disposable Bioreactor

    Designed for high-yield monoclonal antibody production

    Corningâ„¢ CELLine Disposable Bioreactor

    Thermo Scientificâ„¢ CentriPAK BPC Sterilized Single-Use for Sorvall BIOS 16 Bioprocessing Centrifuge

    Reduce cross-contamination risk while separating cell cultures

    Thermo Scientificâ„¢ CentriPAK BPC Sterilized Single-use for Sorvall BIOS 16 Bioprocessing Centrifuge

    Corningâ„¢ Disposable Roller Bottles

    Manufactured from optically clear polystyrene for excellent visibility and tissue culture-treated for optimal cell attachment

    Corningâ„¢ Disposable Roller Bottles

    Thermo Scientificâ„¢ Labtainerâ„¢ Pro BioProcess Container with BioTitan Retention

    Ideal for sample preparation, cell culture processes, storage, and transport

    Thermo Scientificâ„¢ Labtainerâ„¢ Pro BioProcess Container with BioTitan Retention, CX5-14, 3 ports, end-ported with AseptiQuik G connectors and body needleless luer lock

    Featured Products

    Placeholder

    Catalog Number 17815716

    Thermo Scientificâ„¢ Labtainerâ„¢ BioProcess Container (BPC), 10L with 3 Ports, Luer Lock, 2D BPC
    Placeholder

    Catalog Number 16480631

    Thermo Scientificâ„¢ Nalgeneâ„¢ PC Platinum Certified Cleanâ„¢ Biotainerâ„¢ Bottle
    Viewing 0-2 of 2

    Essential Categories

    View All Bioprocess System Bags and Liners
    View All Cell Culture Flasks
    View All Media Bottles

    Related Resources


    mAbs Solutions Platform

    With Thermo Fisher Scientific, you have the support you need to push your therapeutic development strategies a step further. Explore our new mAb solutions platform and discover a suite of scalable and robust solutions for all stages of the mAbs development workflow.

    Discover More
    mAbs Solutions Platform

    mAbs Process Playbook

    Explore each operations unit in the mAb Process Playbook to learn how to utilize our standard and modular single-use manifolds.

    View Interactive Brochure
    mAbs Process Playbook

    Eppendorf Centrifuges for mAbs Discovery Workflow

    Antibody development poses challenges, with time and budget constraints. Optimizing each production step, from transfection to scale-up, is crucial. Eppendorf offers solutions, expertise, and tools to enhance antibody yield and quality, ensuring a competitive edge.

    Download mAbs Discovery Workflow
    Eppendorf Centrifuges for mAB Discovery Workflow

    Stevanato Group EZ-fillâ„¢ Vials

    DWK Life Sciences offers the market’s most established choice for pre-sterilized containers helping to ensure flexible and streamlined processability.

    Learn More
    Stevanato Group EZ-fillâ„¢ Vials

    BioPharma Workflow Solutions

    For scientists pursuing robust and reproducible methods when working with biopharmaceuticals, selecting the correct workflow is imperative for success in quantitating and quality assuring APIs.

    Read More
    BioPharma Workflow Solutions

    The Rise of Monoclonal Antibodies as Blockbuster Drugs

    In 2018, seven out of the top ten best-selling drugs were monoclonal antibodies, including AbbVie's highly successful therapy Humira (adalimumab) for immune disorders. Discover the function, challenges, and future of mAbs in our lab reporter article.

    Read More
    The Rise of Monoclonal Antibodies as Blockbuster Drugs

    Monoclonal Antibody Production


    Monoclonal antibodies (mAbs) have revolutionized medicine since their inception in 1975 by Köhler and Milstein. With 162 approved therapies targeting various diseases, including cancer and infections, mAbs have become highly effective and top-selling drugs. They are also being investigated for autoimmune, neurodegenerative, and cardiovascular conditions due to their versatility and specificity. However, the development and production of mAbs poses challenges, requiring significant time, resources, and complex manufacturing operations. The Fisher Scientific channel offers advanced solutions to streamline the development process and ensure cost-effective antibody production for all steps from cell line development to final fill.

    Frequently Asked Questions


    What Is a Monoclonal Antibody?

    Monoclonal antibodies are laboratory-produced molecules engineered to serve as substitute antibodies in fighting disease. They mimic the body's natural immune response and target foreign agents.

    What Is the Most Used Cell Platform for mAb Development?

    The most widely used cell platform for mAb development is the Chinese Hamster Ovary (CHO) cell line. CHO cells have become the preferred host for mAb production due to their genetic stability, high protein expression levels, ability to perform post-translational modifications similar to human cells, scalability, and regulatory approval for commercial production. The CHO cell line has a long history of safe use in biopharmaceutical manufacturing and offers a robust infrastructure with established protocols and knowledge base, making it an efficient and reliable platform for mAb development.

    What Are the Challenges of mAbs Development?

    Challenges in mAbs development include time and resource requirements, labor-intensive processes from identifying suitable target antigens to generating high-affinity antibodies, stringent manufacturing control and optimization, and high costs associated with production, research, and development.

    Contact Us


    Talk to a Sales Representative

    If you have questions regarding to our products, services and offers, or should you require technical assistance, please request a call-back to be contacted by our Specialist Sales Representative.

    Request a Call Back
    Talk to a Sales Representative

    Talk to a Safety Specialist

    Contact us today to talk about any safety issues or to advise on product selection.

    Contact Us
    Talk to a Safety Specialist

    Fisher Scientific Biotech News

    Join our mailing list and receive updates on new product announcements, special promotions, sales and more.

    Sign Up Now
    Fisher Scientific Biotech News

    Top Brands


    Thermo Scientific Logo
    Fisherbrand
    Gibco logo
    invitrogen_logo
    Kimberly Clark Logo
    BINDER inc. logo
    Merck Logo
    Mp Bio Logo
    Viewing 1-6 of 10
    About Us
    Fisher Scientific
    Quality Management
    Work at Thermo Fisher Scientific
    Customer Support
    Help & Support Center
    Returns
    Account Dashboard
    Report a Site Issue
    Business Solutions
    Biopharma
    Biotech
    Industry
    Green Solutions
    Programs & Services
    Edge Program
    New Lab Start-Up Program
    SureTRACE Program
    SureTRACE+ Program
    Sustainability Program
    Unity Lab Services
    Connect with Us
    Lab Reporter
    News Corner
    Subscribe to News
    Webinars
    Facebook icon Facebook icon LinkedIn icon LinkedIn icon YouTube Icon YouTube Icon
    Fisher Scientific - part of Thermo Fisher Scientific

    We keep science moving forward by offering over 2.6 million products and extensive support services to the research, production, testing laboratories, healthcare, and science education markets. Count on us for an unrivaled selection of lab, life sciences, safety, and facility management supplies—including chemicals, consumables, equipment, instruments, diagnostics, and much more—along with exceptional customer care from an industry-leading team that’s proud to be part of Thermo Fisher Scientific.

    Cookie Preferences
    Website Terms & Conditions
    Sales Terms & Conditions
    Privacy Information Center
    Cancellation and Returns Policy
    How Cookies are Used

    Fisher Scientific - Lagoas Park, Edificio 8 - Piso 0 - 2740-265 Porto Salvo
    NIF : 506429210
    © 2025 Thermo Fisher Scientific Inc. All rights reserved.
    All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
    Facebook icon Facebook icon LinkedIn icon LinkedIn icon YouTube Icon YouTube Icon

    Your choices regarding cookies on this site

    We and our affiliates and vendors use cookies and similar technologies to operate our sites, recognize visitors to our sites, provide secure log-in, collect statistics to optimize site functionality, and deliver content tailored to your interests. Click Accept All to accept all cookies and go directly to the site, or click on Manage Settings to see detailed descriptions of the types of cookies and choose whether to accept certain cookies while on the site.