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Thermo Scientific™ TheraPure™ 2'-Fluoro-Ac-C Phosphoramidite, serum vial bottle
2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis.
Marke: Thermo Scientific™ 27-1604-02
18.23 EUR valid until 2024-12-20
Use promo code "21651" to get your promotional price.
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Beschreibung
2'-Fluoro-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-fluorocytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C41H49N5FO8P
• Base: C
• Base Protection: Ac
• Formula weight: 789.8 g/mol
• CAS number: 159414-99-0
• HPLC purity: >98%
• 31P NMR purity: ≥98%
Spezifikation
| AKTA Synthesizers, Applied Biosystems Synthesizers | |
| Store in freezer (at or below -20°C). | |
| 2in-Fluoro modified, Fast deprotection | |
| 98% | |
| Phosphoramidite | |
| RNA | |
| Powder |
| 2in-Fluoro-Ac-C CEP | |
| Cytidine (C) | |
| Room Temperature | |
| 1 g | |
| TheraPure™ | |
| TheraPure™ |
For Research Use Only. Not for use in diagnostic procedures.