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Thermo Scientific™ TheraPure™ 2'-Fluoro-U Phosphoramidite, 20-400 finish bottle

2'-Fluoro-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1602-09

Product Code. 17907192

  • 11.70€ / 0.25g

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Description

Description

2'-Fluoro-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-2'-fluorouridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C39H46FN4O8P
• Base: A
• Formula weight: 748.8 g/mol
• CAS number: 146954-75-8
• HPLC purity: >98%
• 31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Expedite Synthesizers
Store in freezer (at or below -20°C).
2in-Fluoro modified
98%
Phosphoramidite
RNA
Powder
2in-Fluoro-U CEP
Uridine (U)
Room Temperature
0.25 g
TheraPure™
TheraPure™
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Lot Number Certificate Type Date Catalog Number
Lot NumberYE1442 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1602-09
Lot NumberZA3702 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog Number27-1602-09
Lot NumberZD1462 Certificate TypeCertificate of Analysis Date26/01/2025 Catalog Number27-1602-09
Lot NumberZE2032 Certificate TypeCertificate of Analysis Date26/01/2025 Catalog Number27-1602-09
Lot NumberZL2162 Certificate TypeCertificate of Analysis Date25/01/2025 Catalog Number27-1602-09
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Thermo Scientific™ TheraPure™ 2'-Fluoro-U Phosphoramidite, 20-400 finish bottle > 0.25 g

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