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5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals Product Code.: 11330528
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5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals

Product Code. 11330528
5 g
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Quantity:
250 mg
1 g
5 g
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Product Code. 11330528

Brand: Thermo Scientific Alfa Aesar 043853.06

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Description

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 491-80-5
Molecular Formula C16H12O5
Molecular Weight (g/mol) 284.27
MDL Number MFCD00006839
InChI Key WUADCCWRTIWANL-UHFFFAOYSA-N
Synonym biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenylShow MoreShow Less
PubChem CID 5280373
ChEBI CHEBI:17574
IUPAC Name 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
SMILES COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

Specifications

Melting Point 210°C to 213°C
Quantity 5 g
Beilstein 278107
Solubility Information Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
Formula Weight 284.27
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 5,7-Dihydroxy-4'-methoxyisoflavone

Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberT02A059 Certificate TypeCertificate of Analysis Date12/04/2022 Catalog Number043853.03,043853.06,043853.MD
Lot NumberC23X034 Certificate TypeCertificate of Analysis Date07/12/2021 Catalog Number043853.03,043853.06,043853.MD
Lot NumberJ16S041 Certificate TypeCertificate of Analysis Date29/11/2021 Catalog Number043853.03,043853.06,043853.MD
Lot NumberB27S028 Certificate TypeCertificate of Analysis Date23/11/2021 Catalog Number043853.03,043853.06,043853.MD
Lot NumberG29P24 Certificate TypeCertificate of Analysis Date23/11/2021 Catalog Number043853.03,043853.06,043853.MD

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