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ACET, Tocris Bioscience™
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Quantity:
10 mg
Description
Potent and selective GluK1 (formerly GluR5) containing kainate receptor antagonist (IC50 = 7 nM) that displays selectivity over GluK2 (formerly GluR6) containing kainate, NMDA, AMPA and group I mGlu receptors. Reversibly blocks induction of NMDA receptor-independent long term potentiation (LTP) in vitro at nanomolar concentrations.
Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Specifications
Specifications
CAS | 936095-50-0 |
Molecular Formula | C20H21N3O6S |
Quantity | 10 mg |
Synonym | (S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-yl-methyl)-5-methylpyrimidine-2, 4-dione |
InChI Key | OAAMYRWMIRGBQF-UHFFFAOYSA-N |
SMILES | CC1CN(C(=O)N(C1=O)CC2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)CC(C(=O)O)N |
IUPAC Name | 3-[[3-(2-amino-2-carboxyethyl)-5-methyl-2,6-dioxo-1,3-diazinan-1-yl]methyl]-5-phenylthiophene-2-carboxylic acid |
Molecular Weight (g/mol) | 431.463 |
PubChem CID | 118797384 |
Formula Weight | 429.45 |
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