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CD3 Mouse anti-Human, PE, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Brand: BD Biosciences 555333

Product Code. 15888068

255.00€ / Each

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Description

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Specifications

Antigen	CD3
Classification	Monoclonal
Conjugate	PE
Host Species	Mouse
Purification Method	Affinity Purified
Regulatory Status	RUO
Primary or Secondary	Primary
Content And Storage	Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications	Flow Cytometry
Clone	UCHT1
Formulation	Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen	Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity	100 Tests
Research Discipline	Immunology
Target Species	Human
Isotype	IgG1 κ

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CD3 Mouse anti-Human, PE, Clone: UCHT1, BD

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