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CD47 Mouse anti-Human, NA/LE, Unlabeled, Clone: B6H12, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 556043
380.10 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.
Description
Reacts with a 42-52kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications
CD47 | |
Monoclonal | |
1.0mg/mL | |
IAP; CDw149; gp42; MER6; Neurophilin; OA3 ; Rh-related antigen | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C |
Flow Cytometry | |
B6H12 | |
Unconjugated | |
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. | |
Purified human placental RGD-binding proteins | |
0.5 mg | |
Immunology | |
Human | |
IgG1 κ |
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