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Paxillin Mouse, Unlabeled, Clone: 349, BD
Mouse Monoclonal Antibody
436.00€ - 675.00€
Specifications
| Antigen | Paxillin |
|---|---|
| Clone | 349 |
| Concentration | 1.0mg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15845229
|
BD Biosciences
610051 |
50 μg |
436.00€
1 set |
Estimated Shipment: 22-11-2024
Log in to see stock. |
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|
15855229
|
BD Biosciences
610052 |
150 μg |
675.00€
1 set |
Estimated Shipment: 29-11-2024
Log in to see stock. |
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Description
A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts. One of these is the 68 kDa paxillin protein. Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers. It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells. Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa. It binds to the rod domain of vinculin, another focal adhesion protein. It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation.Specifications
| Paxillin | |
| 1.0mg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing glycerol and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 349 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Chicken, Human, Mouse, Rat | |
| Chicken Paxillin aa. 1 to 557 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.