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TCR β Chain Hamster anti-Mouse, Brilliant Violet 421, Clone: H57-597, BD
Hamster Monoclonal Antibody
Brand: BD Biosciences 562839
291.55 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.
This item is not returnable.
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Description
The H57-597 antibody reacts with a common epitope of the β chain of the T-cell Receptor (TCR) complex on αβ TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδ TCR-bearing T cells. In the fetal and adult thymus, the TCR β-chain may form homodimers or pair with the pre-TCR α-chain on the surface of immature thymocytes before expression of the TCR α-chain. Plate-bound or soluble H57-597 antibody activates αβ TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.
Host Species: Hamster
Clone: H57-597
Isotype: IgG2, λ 1
Species Reactivity: Ms
Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Flow Cytometry
Specifications
| TCR β Chain | |
| Monoclonal | |
| 0.2mg/mL | |
| Tcrb; TCRbeta; TCRβ, T cell receptor beta chain | |
| Hamster | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2 |
| Flow Cytometry | |
| H57-597 | |
| Brilliant Violet 421 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| TCR affinity-purified from mouse T-cell hybridoma DO-11.10 | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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Product Title
TCR β Chain Hamster anti-Mouse, Brilliant Violet 421, Clone: H57-597, BD > 50μg; Brilliant Violet 421
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