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API-1, Tocris Bioscience™ Product Code.: 18015342
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API-1, Tocris Bioscience™

Product Code. 18015342
10 mg
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Quantity:
10 mg
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Product Code. 18015342

Brand: Tocris Bioscience 3897/10

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Description

Selective Akt/PKB inhibitor. Antitumor

Akt/protein kinase B (PKB) inhibitor. Binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation. Inhibits EGF-induced kinase activity of Akt1, Akt2 and Akt3. Induces cell growth arrest and apoptosis in human cancer cells expressing constitutively active Akt. Displays antitumor activity in vitro and in vivo.
TRUSTED_SUSTAINABILITY

Specifications

CAS 36707-00-3
Molecular Formula C13H15N5O6
Quantity 10 mg
Synonym api-1, 4-amino-8-3,4-dihydroxy-5-hydroxymethyl oxolan-2-yl-5-oxo, 4-amino-5,8-dihydro-5-oxo-8-?-d-ribofuranosyl-pyrido 2,3-d pyrimidine-6-carboxamide, 4-amino-5,8-dihydro-5-oxo-8-beta-d-ribofuranosyl-pyrido 2,3-d pyrimidine-6-carboxamide, 4-amino-8-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl oxolan-2-yl-5-oxopyrido 2,3-d pyrimidine-6-carboxamide
InChI Key SPBWHPXCWJLQRU-FITJORAGSA-N
SMILES C1=C(C(=O)C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)C(=O)N
IUPAC Name 4-amino-8-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-oxopyrido[2,3-d]pyrimidine-6-carboxamide
Molecular Weight (g/mol) 337.292
PubChem CID 24773090
Formula Weight 337.29
Percent Purity >96%
Chemical Name or Material API-1
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