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ATR Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA585507

Additional Details : Weight : 0.01000kg

Product Code. 16322445

  • 472.00€ / 100µL
Estimated Shipment: 01-08-2024
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Description

Description

Keep as concentrated solution. Positive Control: 293T, A431, HeLa, HepG2, Raji, Raji NE, Raji nuclear extract. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Specifications

Specifications

ATR
Polyclonal
Unconjugated
ATR
2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8
Rabbit
Antigen affinity chromatography
RUO
245000, 545
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Q13535, Q9JKK8
ATR
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATR.
100 μL
Primary
Human, Mouse
Antibody
IgG
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