missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
Brand: Tocris Bioscience™ 5141/10
232.39 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
View return policy
Description
AZD 5582 dihydrochloride is a dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.Specifications
| >97% | |
| AZD 5582 dihydrochloride | |
| AZD 5582 dihydrochloride |
| 10 mg | |
| 1088.21 |
For Research Use Only