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Tocris Bioscience™ BIBO 3304 trifluoroacetate
Highly selective NPY Y1 receptor antagonist
Brand: Tocris Bioscience™ 2412/10
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Description
BIBO 3304 trifluoroacetate is a high affinity NPY Y1 receptor antagonist (IC50 values are 0.38 and 0.72 nM at human and rat receptors respectively) that displays > 2600-fold selectivity over Y2, Y4 and Y5 receptors. Inhibits NPY - and fasting-induced feeding in vivo following central administration. Also antagonizes anxiolytic-like effects of NPY.Specifications
N-[(1R)-1-[[[[4-[[(Aminocarbonyl)amino]methyl]phenyl]methyl]amino]carbonyl]-4-[(aminoiminomethyl)amino]butyl]-α-phenyl-benzeneacetamide ditrifluoroacetate | |
>98% | |
Soluble to 100mM in DMSO | |
Observed MW: 757.69 |
2310085-85-7 | |
10 mg | |
C29H35N7O3.2CF3CO2H |
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