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Corning™ Bovine Calf Serum, Iron-Fortified, US Origin
Bovine calf serum is a cost-effective alternative to Fetal Bovine Serum (FBS). It is often used with robust cell lines when large quantities of serum are needed such as in the manufacturing of biological drugs and vaccines. Bovine calf serum is derived from calves that are generally less than 22 weeks old. It has very high levels of transferrin, which allows for iron fortification to levels of more than three times greater than FBS.
Brand: Corning™ 35-053-CM
Description
All Corning bovine calf serum is collected under direct supervision using Corning’s strict collection protocol. These controls ensure we can meet a strict endotoxin level of ≤10 EU/mL and hemoglobin levels of ≤25 mg/dL.
All Corning bovine calf serum is collected in USDA inspected facilities in the United States and is derived from healthy calves that have passed ante- and post-mortem inspection and were found to be free of contagious diseases.
Filtering Standards Industry standards are to filter bovine calf serum through a 0.2 μm filter. Corning goes above the industry standard using triple 0.1 μm sterile filters for all our bovine calf serum. This is the same filtering requirements Corning uses for FBS products, which provides a Sterility Assurance Level (SAL) of 10-3.
In addition to USP and EP 2.6.1 sterility testing, all lots must test negative for mycoplasma. When used in the correct application, Corning bovine calf serum can perform as well as, or better than, FBS at a fraction of the cost. Iron Fortification Calves are often fed a low iron diet. To counter the iron deficiency found in the serum, all Corning bovine calf serum is iron-fortified to bring the iron back to naturally occurring levels. We specify that iron saturation must be between 70%-80%. Total iron binding capacity and percent iron saturation are reported on every Certificate of Analysis.
True Pooled Sterile Filtered All Corning bovine calf serum is true-pooled after filtration to ensure consistency from bottle to bottle within a lot. True-pooling greatly reduces intra-lot variability.
Specifications
-25°C to -15°C | |
United States | |
1000 mL | |
Iron-fortified |
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