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CD63 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen CD63
Concentration 0.26 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16864245
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Proteintech
25682-1-AP-20UL
20 μL
145.00€
20µL
In Stock
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16854245
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Proteintech
25682-1-AP-150UL
150 μL
410.00€
150µL
In Stock
to see stock.
Add to basket
 
Description

Description

CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
Specifications

Specifications

CD63
Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Unconjugated
Rabbit
Human
P08962
967
CD63 Fusion Protein Ag19690
Primary
-20°C
CD63
0.26 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CD63, CD63 antigen, CD63 molecule, Granulophysin, LAMP 3, ME491, MLA1, OMA81H, Tetraspanin 30, Tspan 30, TSPAN30
CD63
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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