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  6. 18015382

CGS 9343B, Tocris Bioscience™

Product Code. 18015382
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Quantity:
10 mg
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Description

Calmodulin antagonist

Calmodulin antagonist; inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Also prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR.

Specifications

CAS 109826-27-9
Molecular Formula C30H32N4O6
MDL Number MFCD04113002
Quantity 10 mg
Synonym 1,3-dihydro-1-1-4-methyl-4h,6h-pyrrolo 1,2-a 4,1-benzoxazepin-4-yl methyl-4-piperidinyl-2h-benzimidazol-2-one maleate
InChI Key NGODOSILXOFQPH-BTJKTKAUNA-N
SMILES OC(=O)\C=C/C(O)=O.CC1(CN2CCC(CC2)N2C(=O)NC3=CC=CC=C23)OCC2=CC=CC=C2N2C=CC=C12
IUPAC Name (2Z)-but-2-enedioic acid; 1-[1-({7-methyl-8-oxa-2-azatricyclo[8.4.0.0²,⁶]tetradeca-1(14),3,5,10,12-pentaen-7-yl}methyl)piperidin-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-one
Molecular Weight (g/mol) 544.61
PubChem CID 14171586
Formula Weight 544.61
Percent Purity >98%
Chemical Name or Material CGS 9343B
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