missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Indoles and derivatives
  7. CI 988, Tocris Bioscience™

CI 988, Tocris Bioscience™

Product Code. 18074202
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective CCK2 antagonist

Potent and selective CCK2 (CCK-B) receptor antagonist that displays ∽ 1600-fold selectivity over CCK1 receptors (IC50 values are 1.7 and 2717 nM for CCK2 and CCK1 respectively). Has negligible affinity at a range of other binding sites (IC50 > 10 μM). Exhibits anxiolytic activity following oral administration.

Chemical Identifiers

CAS 130332-27-3
Molecular Formula C35H42N4O6
Molecular Weight (g/mol) 614.743
InChI Key FVQSSYMRZKLFDR-ZABPBAJSSA-N
Synonym unii-2637pdx9si, 3-1r-2-2r-2-2-adamantyloxycarbonylamino-3-1h-indol-3-yl-2-methyl-propanoyl amino-1-phenyl-ethyl carbamoyl propanoic acid, 4-1r-2-2r-2-2-adamantyloxycarbonylamino-3-1h-indol-3-yl-2-methylpropanoyl amino-1-phenylethyl amino-4-oxobutanoic acid, 4-1r-2-2r-3-1h-indol-3-yl-2-methyl-1-oxo-2-tricyclo 3.3.1.13,7 dec-2-yloxy carbonyl amino propyl amino-1-phenylethyl amino-4-oxobutanoic acid, gtpl873, butanoic acid, 4-1r-2-2r-3-1h-indol-3-yl-2-methyl-1-oxo-2-tricyclo 3.3.1.1 3,7 dec-2-yloxy carbonyl amino propyl amino-1-phenylethyl amino-4-oxo, r-r*,r*-4-2-3-1h-indol-3-yl-2-methyl-1-oxo-2-tricyclo 3.3.1.13,7 dec-2-yloxy carbonyl amino propyl amino-1-phenylethyl amino-4-oxobutanoic acid, 3-1r-2-2r-2-1h-indol-3-ylmethyl-2-1r,3r,5r,7r-adamantan-2-yloxy carbonyl amino propanamido-1-phenylethyl carbamoyl propanoic acid, 3-1r-2-2r-2-adamantan-2-yloxy carbonyl amino-2-1h-indol-3-ylmethyl propanamido-1-phenylethyl carbamoyl propanoic acid, 4-r-2-r-2-adamantan-2-yloxy carbonyl amino-3-1h-indol-3-yl-2-methylpropanamido-1-phenylethyl amino-4-oxobutanoic acid
PubChem CID 108187
IUPAC Name 4-[[(1R)-2-[[(2R)-2-(2-adamantyloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]amino]-1-phenylethyl]amino]-4-oxobutanoic acid
SMILES CC(CC1=CNC2=CC=CC=C21)(C(=O)NCC(C3=CC=CC=C3)NC(=O)CCC(=O)O)NC(=O)OC4C5CC6CC(C5)CC4C6

Specifications

Quantity 50 mg
Formula Weight 614.73
Percent Purity >99%
Chemical Name or Material CI 988
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.