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CRALBP Recombinant Rabbit Monoclonal Antibody (HL1833), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Thermo Scientific MA550338
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Description
Cellular retinaldehyde-binding protein (CRALBP) plays an important role in the regeneration of 11-cis-retinal for use in rod visual pigments such as opsin and rhodopsin. Once 11-cis-retinal is photoisomerized in the rod outer segment, it is converted to all-trans-retinal and further modified into all-trans-retinol. All-trans-retinol then diffuses into the retinal pigment epithelium (RPE) to be converted back to 11-cis-retinol and further oxidized into 11-cis-retinal (both by CRALBP). Genetic mutations involving CRALBP's lack of function have been linked to visual disease such as bothnia dystrophy, retinitis punctata albescens, retina pigmentosa, and Newfoundland rod-cone dystrophy. The presence of CRALBP serves as a marker for RPE and Muller glial cells of the retina.
Specifications
CRALBP | |
Recombinant Monoclonal | |
1 mg/mL | |
PBS with no preservative | |
Q9Z275 | |
RLBP1 | |
Recombinant fragment of human CRALBP. | |
100 μL | |
Primary | |
Mouse, Rat | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
HL1833 | |
Unconjugated | |
RLBP1 | |
3110056M11Rik, cellular retinaldehyde-binding protein, cellular retinaldehyde-binding protein-1, CRALBP, retinaldehyde binding protein 1, retinaldehyde-binding protein 1, retinaldehyde-binding protein precursor, Rlbp1 | |
Rabbit | |
Protein A | |
RUO | |
19771, 293049 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
IgG |
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Product Title
CRALBP Recombinant Rabbit Monoclonal Antibody (HL1833), Invitrogen™ > 100 μL; Unconjugated
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