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Thermo Scientific™ DMF-dG Phosphoramidite, standard grade, serum vial bottle

DMF-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Dimethylaminoformamidine (DMF) base protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1737-07

Product Code. 18004060

  • 18.70€ / 2g
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Description

Description

DMF-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Dimethylaminoformamidine (DMF) base protection, for use in oligonucleotide synthesis. DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process and produce the highest amount of full length product. Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide. By using Ac-dC, Bz-dA, and DMF-dG monomers, fast cleavage and deprotection can be effected by a 1:1 mixture of aqueous ammonium hydroxide and aqueous methylamine (or AMA) in 10 min. This product is supplied in a 60 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

Features:

  • Full chemical name – 5'-O-(4,4'-Dimethoxytrityl)-N2-(dimethylaminoformamidine)-2'-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula – C43H53N8O7P
  • Base – dG
  • Base Protection – DMF
  • Molecular weight – 824.9 g/mol
  • CAS number – 330628-04-1
  • HPLC Purity – ≥98.0%; M-11 Impurity ≤0.01%
  • 31P NMR Purity – ≥98.0%; Sum of non-primary peaks at 140-152 ppm (PIII impurities): ≤1.5%
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Powder
DMF-dG CEP
Deoxyguanosine (dG)
Room Temperature
2 g
Standard
AKTA Synthesizers, Applied Biosystems Synthesizers
Store in freezer (at or below -20°C).
Fast deprotection
98%
Phosphoramidite
DNA
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Lot Number Certificate Type Date Catalog Number
Lot NumberXA1802 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1737-07
Lot NumberXB1032 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1737-07
Lot NumberWK1212 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1737-07
Lot NumberWL5192 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1737-07
Lot NumberXD1332 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1737-07
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