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Tocris Bioscience™ DSPE-PEG 2000 Maleimide
PEGylated DSPE with a maleimide reactive group
Brand: Tocris Bioscience™ 7947/10
181.42 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
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Description
DSPE-PEG (2000) maleimide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with a maleimide-terminated end. It is used to synthesize antibody-coupled PEG (2000)-DSPE micelles that can be transferred into liposomes to generate immunoliposomes. DSPE-PEG (2000) maleimide can also be incorporated into the outer membrane of lipid nanoparticles (LNPs) for further bioconjugation. It is used in antibody-targeted LNP-mRNA systems to generate transient antifibrotic chimeric antigen receptor (CAR) T cells in vivo.Specifications
| 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)] | |
| Lipid Nanoparticles | |
| 90% |
| 10 mg | |
| (C2H4O)nC51H91N3O13P.NH4 or Na |