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Thermo Scientific™ Exonuclease III (200 U/μL)

Digest double-stranded DNA or DNA-RNA hybrids with Exonuclease III is a 3'–>5' exonuclease.

Brand:  Thermo Scientific™ EN0191

26.25 EUR valid until 2025-04-18
Use promo code "24107" to get your promotional price.

Product Code. 10858990

  • 36.97€ / 4000 units

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Description

Description

Exonuclease III (ExoIII) exhibits four catalytic activities (see Reference1). The 3'≥5' exodeoxyribonuclease activity of ExoIII is specific for double-stranded DNA. ExoIII degrades dsDNA from blunt ends, 5'-overhangs or nicks, releases 5'-mononucleotides from the 3'-ends of DNA strands and produces stretches of single-stranded DNA. It is not active on 3'-overhang ends of DNA that are at least four-bases long and do not carry a 3'-terminal C-residue (see Reference 2) on single-stranded DNA, or on phosphorothioate-linked nucleotides.

ExoIII 3'-phosphatase activity removes the 3'-terminal phosphate, generating a 3'-OH group. ExoIII Rnase H activity exonucleolytically degrades the RNA strand in RNA-DNA hybrids. ExpOOO apurinic/apyrimidinic-endonuclease activity cleaves phosphodiester bonds at apurinic or apyrimidinic sites to produce 5'-termini that are base-free deoxyribose 5'-phosphate residues.

Highlights

  • Active in restriction enzyme buffers
TRUSTED_SUSTAINABILITY
Specifications

Specifications

200 U/μL
Enzyme Buffer
Exonuclease III
Exonuclease
4,000 units
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Product Information

Manuals

User Guide: Exonuclease III (Exo III) Version: B.00 File size: 219.6 kB
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot Number2838240 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog NumberEN0191
Lot Number2838297 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog NumberEN0191
Lot Number2895224 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog NumberEN0191
Lot Number2897336 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog NumberEN0191
Lot Number2906750 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog NumberEN0191
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Thermo Scientific™ Exonuclease III (200 U/μL) > 200U/μL, 4000U

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For Research Use Only. Not for use in diagnostic procedures.