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Thermo Scientific™ EZ-Link™ Psoralen-PEG3-Biotin

Biotinylate DNA or RNA via intercalation and conjugation with thymine- and other pyrimidine-containing bases with this light-activated biotinylation reagent.

Brand:  Thermo Scientific™ 29986

Product Code. 10648294

  • 370.00€ / 5mg
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Description

Description

Thermo Scientific™ EZ-Link Psoralen-PEG3-Biotin enables biotinylation of DNA or RNA via UV-light-activated intercalation of the psoralen group with thymine- and other pyrimidine-containing bases to form covalent bonds.

Highlights:

  • Water-soluble, polyethylene glycol (PEG) spacer arm
  • Much higher coupling yield than achieved with photoactivatable biotin
  • Psoralen moiety reacts through a cyclo-addition mechanism with the 5,6 double bond in thymine- and other pyrimidine-containing bases
  • Covalent attachment occurs with exposure to UV light (approximately equal to 350nm)
  • Great for biotinylating DNA/RNA probes (∽1 biotin/10-20 bases)
  • Ultrahigh sensitivity relative to radiolabeled probes (<100 femtograms)
  • Does not interfere with hybridization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Psoralen-PEG3-Biotin
Store at 4°C protected from light and moisture. Shipped at ambient temperature.
Cell-Impermeant
Psoralen
Biotin
Biotin & Analogs
5 mg
EZ-Link™
Light-activated
DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water
Extra-long, Pegylated
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For Research Use Only. Not for use in diagnostic procedures.