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FK 228, Tocris Bioscience™
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Quantity:
1 mg
Description
Potent and selective inhibitor of class I histone deacetylases (HDACs) (IC50 values are 36, 47, 510 and 14,000 nM for HDAC1, HDAC2, HDAC4 and HDAC6 respectively). Exhibits cytotoxicity against various human tumor cell lines; also exhibits antitumor activity against human tumor xenografts.
Specifications
Specifications
CAS | 128517-07-7 |
Molecular Formula | C24H36N4O6S2 |
Quantity | 1 mg |
Synonym | romidepsin |
InChI Key | OHRURASPPZQGQM-OYTWCIJESA-N |
SMILES | CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C |
IUPAC Name | (1S,7Z,10S,16Z)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone |
Molecular Weight (g/mol) | 540.694 |
PubChem CID | 123135747 |
Formula Weight | 540.7 |
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