missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Carbohydrates
  5. Monosaccharides
  6. Fludarabine, Tocris Bioscience™

Fludarabine, Tocris Bioscience™

Product Code. 18782624
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Purine analog; inhibits DNA synthesis

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.

Chemical Identifiers

CAS 21679-14-1
Molecular Formula C10H12FN5O4
Molecular Weight (g/mol) 285.24
MDL Number MFCD00132942
InChI Key HBUBKKRHXORPQB-FJFJXFQQSA-N
Synonym fludarabine, f-ara-a, 2-fluoro ara-a, 9-beta-d-arabinofuranosyl-2-fluoroadenine, fludarabine inn, fludarabinum latin, fludarabina spanish, fludarabina, fludarabinum, 2r,3s,4s,5r-2-6-amino-2-fluoro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol
PubChem CID 657237
IUPAC Name (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
SMILES NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)C2=NC(F)=N1

Specifications

Quantity 10 mg
Formula Weight 285.23
Percent Purity >99%
Chemical Name or Material Fludarabine
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.