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Description
Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.

Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 285.23 |
Percent Purity | >99% |
Chemical Name or Material | Fludarabine |
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Fludarabine, Tocris Bioscience™ >
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