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  8. Fumonisin B1, 96%, Thermo Scientific Chemicals

Fumonisin B1, 96%, Thermo Scientific Chemicals

Product Code. 10741361
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Quantity:
1 mg
5 mg

Description

Fumonisin, CAS # 116355-83-0, also known as Macrofusine, is a cell permeable mycotoxin that is an inhibitor of sphingosine N-acetyl transferase.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Fumonisin is a fungal metabolite that is a cell permeable mycotoxin that can halt sphingolipid biosynthesis by inhibiting sphingosine N-acetyl transferase

Applications

• It can potently inhibit sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases

• It is also a protein serine and threonine phosphatase inhibitor

• It can selectively inhibit sphingomyelin biosynthesis in neuronal cells

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 116355-83-0
Molecular Formula C34H59NO15
Molecular Weight (g/mol) 721.8
MDL Number MFCD00133349
InChI Key UVBUBMSSQKOIBE-UWCNXKJPSA-N
Synonym macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid
PubChem CID 16760030
IUPAC Name (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
SMILES CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O

Specifications

Color Tan to White
Elemental Analysis 55.00 to 58.00%C, 1.60 to 2.20%N
Assay Percent Range 95% min. (HPLC)
Quantity 1 mg
Merck Index 15, 4318
Solubility Information Solubility in water: soluble. Other solubilities: soluble in methanol,acetonitrile
Formula Weight 721.8
Percent Purity 96%
Physical Form Powder
Chemical Name or Material Fumonisin B1

Safety and Handling

compliance-icons
Product Identifier
  • Fumonisin B1
 Signal Word
  • Warning
 Hazard Category
  • Carcinogenicity Category 2
 Hazard Statement
  • H351-Suspected of causing cancer.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only

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