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GGTI 298, Tocris Bioscience™ Product Code.: 18054182

GGTI 298, Tocris Bioscience™

Product Code. 18054182
1 mg
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Quantity:
1 mg
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Product Code. 18054182

Brand: Tocris Bioscience 2430/1

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This item is not returnable. View return policy

Geranylgeranyltransferase I (GGTase I) inhibitor

CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor. Strongly inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50 values are 3 and > 10 μM respectively). Causes G0-G1 cell cycle block and apoptosis in A549 cells and inhibits cell invasion and migration in COLO 320CM cells.
TRUSTED_SUSTAINABILITY

Specifications

CAS 1217457-86-7
Molecular Formula C29H34F3N3O5S
Synonym ggti 298, ggti298 trifluoroacetate, ggti 298 tfa salt, ggti-298 tfa salt, ggti 298 tfa, ggti 298 trifluoroacetate salt hydrate, tfa, ggti 298 trifluoroacetate salt hydrate hplc , film, n-4-2-r-amino-3-mercaptopropyl amino-2-naphthylbenzoyl leucine methyl ester trifluoroacetate salt hydrate, n-4-2 r-amino-3-mercaptopropyl amino-2-1-naphthalenyl benzoyl-l-leucine methyl ester trifluoroacetate salt
InChI Key WALKWJPZELDSKT-UFABNHQSSA-N
SMILES CC(C)CC(C(=O)OC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
IUPAC Name methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate;2,2,2-trifluoroacetic acid
Molecular Weight (g/mol) 593.662
Quantity 1 mg
PubChem CID 16078971
Formula Weight 593.66
Percent Purity >95%
Chemical Name or Material GGTI 298
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