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GS 39783, Tocris Bioscience™

Product Code. 30001313
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Positive allosteric modulator of GABAB receptors

Positive allosteric modulator of GABAB receptor function. Potentiates the effects of GABA on [35S]GTPγS binding at recombinant and native GABAB receptors (EC50 values are 2.1 and 3.1μM respectively). Decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines.

Chemical Identifiers

CAS 39069-52-8
Molecular Formula C15H23N5O2S
Molecular Weight (g/mol) 337.442
InChI Key GSGVDKOCBKBMGG-UHFFFAOYSA-N
Synonym n4,n6-dicyclopentyl-2-methylthio-5-nitropyrimidine-4,6-diamine, 4,6-pyrimidinediamine, n,n'-dicyclopentyl-2-methylthio-5-nitro, n,n'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine, n4,n6-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine, pseudoephedrine, +, tocris-2001, gs hplc, n,n'-dicyclopentyl-2-methylthio-5-nitro-4,6-pyrimidinediamine, n4,n6-dicyclopentyl-2-methylthio-5-nitro-4,6-pyrimidinediamine
PubChem CID 6604928
IUPAC Name 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine
SMILES CSC1=NC(=C(C(=N1)NC2CCCC2)[N+](=O)[O-])NC3CCCC3

Specifications

Quantity 10 mg
Formula Weight 337.44
Percent Purity >98%
Chemical Name or Material GS 39783
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