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Tocris Bioscience™ GSK 1562590 hydrochloride

High affinity, selective urotensin II (UT) receptor antagonist

384.00€ - 1535.00€

Specifications

Purity >98%
Product Type GSK 1562590 hydrochloride
Molecular Weight (g/mol) 617.95
Inhibitors GSK 1562590 hydrochloride
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18776139
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Tocris Bioscience™
5110/50
50 mg
1535.00€
50mg
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18785919
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Tocris Bioscience™
5110/10
10 mg
384.00€
10mg
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Description

Description

High affinity and selective urotensin II (UT) receptor antagonist (pKi values are 9.14, 9.28, 9.34, 9.64 and 9.66 at monkey, human, mouse, cat and rat recombinant receptors respectively). Exhibits selectivity for UT receptors over a range of GPCRs, ion channels, enzymes and neurotransmitter transporters. Supresses human urotensin-II (hU-II)-induced contraction of isolated rat aorta in vitro and ex vivo. Inhibits the hU-II-induced increase in mean blood pressure in vivo. Orally active.
Specifications

Specifications

>98%
GSK 1562590 hydrochloride
617.95
GSK 1562590 hydrochloride
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