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Tocris Bioscience™ Hh-Ag1.5
Potent and high affinity Smo receptor agonist
Brand: Tocris Bioscience™ 7807/1
180.56 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
Hh-Ag1.5 is a potent and high affinity Hedgehog (Hh) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay). It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells. Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.Specifications
| 3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide | |
| 1 mg | |
| C28H26ClF2N3OS |
| 612542-14-0 | |
| Smoothened |