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Cytiva HiTrap™ MabSelect™ Prepacked Columns
Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes
1033.00€ - 4200.00€
Specifications
| For Use With (Application) | For fast purification of monoclonal antibodies from large sample volumes, Protein Purification |
|---|---|
| Storage Buffer | 20% Ethanol |
| Content And Storage | 4°C to 30°C |
| Product Code | Brand | Flow Rate | Quantity | Diameter (Metric) Inner Column | Binding Capacity | Price | Quantity & Availability | ||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Flow Rate | Quantity | Diameter (Metric) Inner Column | Binding Capacity | Price | Quantity & Availability | ||
|
11783319
|
Cytiva
28-4082-55 |
<20mL/min. | Each | 1.6 cm | ∼30 mg/mL Human lgG at 2.4 min. residence time |
1033.00€
Each |
In Stock
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||
|
10106234
|
Cytiva
28-4082-58 |
<4 mL/min. | 5 Pk. | 0.7 cm | ∼40 mg/mL Human lgG at 2.4 min. residence time |
1072.00€
Pack of 5 |
In Stock
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||
|
11550634
|
Cytiva
28-4082-61 |
<4 mL/min. | 5 Pk. | 1.6 cm | ∼40 mg/mL Human lgG at 2.4 min. residence time |
4200.00€
Pack of 5 |
In Stock
Log in to see stock. |
||
|
11545135
|
Cytiva
28-4082-56 |
<20mL/min. | 5 Pk. | 1.6 cm | ∼30 mg/mL Human lgG at 2.4 min. residence time |
4200.00€
Pack of 5 |
In Stock
Log in to see stock. |
||
|
10359534
|
Cytiva
28-4082-53 |
<4 mL/min. | 5 Pk. | 0.7 cm | ∼30 mg/mL Human lgG at 2.4 min. residence time |
1072.00€
Pack of 5 |
In Stock
Log in to see stock. |
||
|
11793319
|
Cytiva
28-4082-60 |
<4 mL/min. | Each | 1.6 cm | ∼40 mg/mL Human lgG at 2.4 min. residence time |
1033.00€
Each |
In Stock
Log in to see stock. |
||
Description
Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.
- Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
- High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
- Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
- Designed for use with a syringe, a peristaltic pump, or a chromatography system
MabSelect
- Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
- Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
- Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
- Allows binding from samples with high expression levels of the monoclonal antibody
- Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
- Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
- Permits significant cost savings and extension of cycles in regular production
Specifications
| For fast purification of monoclonal antibodies from large sample volumes, Protein Purification | |
| 20% Ethanol | |
| 4°C to 30°C |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- HiTrap MabSelect, 5 ml
Signal Word
- Warning
Hazard Category
- Flammable liquid Category 3
Hazard Statement
- H226-Flammable liquid and vapour.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P235-Keep cool.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : Ethanol