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Invitrogen™ Human LTF/Lactoferrin ELISA Kit
Human LTF/Lactoferrin quantitates human LTF/Lactoferrin in serum, plasma, supernatant.
Brand: Invitrogen™ EH309RB
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Description
Human LTF/Lactoferrin quantitates human LTF/Lactoferrin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LTF/Lactoferrin.
Lactoferrin (LF) is an iron binding glycoprotein. LF consists of a single polypeptide chain (approximately 80 kDa) folded into two structurally homologous lobes, each of which can reversibly bind one ferric ion (Fe3+). LF is found in external fluids, including milk and mucosal secretions, and is a prominent component of secondary granuals of neutrophils. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Specifications
Bovine Lactoferrin; CKRX; Csp82; epididymis luminal protein 110; GIG12; Growth-inhibiting protein 12; HEL110; HLF2; Kaliocin 1; Kaliocin1; Kaliocin-1; lactoferricin; Lactoferricin H; Lactoferricin-B; Lactoferricin-H; Lactoferrin; lactoferroxin; LactoferroxinA; Lactoferroxin-A; LactoferroxinB; Lactoferroxin-B; LactoferroxinC; Lactoferroxin-C; Lactotransferrin; LF; Lfcin H; Lfcin-B; LfcinH; Lfcin-H; Ltf; minisatellite 10 r detected by probe MMS10; MMS10R; Ms10r; N lobe; neutrophil lactoferrin; talalactoferrin | |
1.96 ng/mL | |
ELISA | |
Colorimetric Microplate Reader | |
LTF | |
<10% | |
HRP | |
Research Use Only | |
2°C to 8°C | |
1 hr 20 min |
1.96 to 480 ng/mL | |
Biotin | |
Plasma, Serum, Supernatant | |
P02788 | |
<12% | |
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
96 Tests | |
Supernatant, 50 μL; Serum, 50 μL; Plasma, 50 μL | |
Lactoferrin | |
4 hr 45 min |