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  7. Hydroxyurea, 98%, Thermo Scientific Chemicals

Hydroxyurea, 98%, Thermo Scientific Chemicals

Product Code. 11469782
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Quantity:
1 g
5 g
25 g
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.

Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 127-07-1
Molecular Formula CH4N2O2
Molecular Weight (g/mol) 76.055
MDL Number MFCD00007943
InChI Key VSNHCAURESNICA-UHFFFAOYSA-N
Synonym hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid
PubChem CID 3657
ChEBI CHEBI:44423
IUPAC Name hydroxyurea
SMILES C(=O)(N)NO

Specifications

Melting Point ∽140°C (decomposition)
Assay Percent Range 98%
Quantity 1 g
Beilstein 1741548
Solubility Information Soluble in water,hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Formula Weight 76.06
Chemical Name or Material Hydroxyurea

Safety and Handling

compliance-icons
Product Identifier
  • Hydroxyurea
 Signal Word
  • Danger
 Hazard Category
  • Germ cell mutagenicity Category 1B
  • Reproductive toxicity Category 1A
 Hazard Statement
  • H340-May cause genetic defects.
  • H360D-May damage the unborn child.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : Hydroxyurea

RUO – Research Use Only

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