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Tocris Bioscience™ INT 131
PPARγ partial agonist
173.00€ - 661.00€
Specifications
| Chemical Name or Material | 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide |
|---|---|
| CAS | 315224-26-1 |
| Target | PPAR gamma/NR1C3 |
| Molecular Formula | C21H12Cl4N2O3S |
| Purity | 0.98 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18709696
|
Tocris Bioscience™
7423/10 |
10 mg |
173.00€
10mg |
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|
18716706
|
Tocris Bioscience™
7423/50 |
50 mg |
661.00€
50mg |
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Description
INT 131 is a potent and selective PPARγ partial agonist (EC50 = 4 nM; Ki = 3.7 nM). It has a 20-fold higher affinity for PPARγ compared with that of Rosiglitazone (Cat. No. 5325). INT 131 improves glucose tolerance in a rodent model of diabetes without inducing hemodynamic and cardiovascular effects. Antidiabetic agent.Specifications
| 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide | |
| PPAR gamma/NR1C3 | |
| 0.98 |
| 315224-26-1 | |
| C21H12Cl4N2O3S |
Safety and Handling
Recommended Storage : Store at -20°C
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Product Title
Tocris Bioscience™ INT 131