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ITPA Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA554614
This item is not returnable.
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Description
Immunogen sequence: GFEDKSAYAL CTFALSTGDP SQPVRLFRGR TSGRIVAPRG CQDFGWDPCF QPDGYEQTYA EMPKAEKNAV SHRFRALLEL QEYFGSLAA Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Specifications
| ITPA | |
| Polyclonal | |
| Unconjugated | |
| ITPA | |
| 2010016I08Rik; AU020102; C20orf37; dJ794I6.3; HAMAP-Rule:MF_03148}; HLC14-06-P; inosine triphosphatase; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); inosine triphosphatase {ECO:0000255; inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphatase {ECO:0000255; inosine triphosphate pyrophosphohydrolase; Itp; ITPA; ITPase; ITPase {ECO:0000255; My049; My049 protein; Non-canonical purine NTP pyrophosphatase; non-canonical purine NTP pyrophosphatase {ECO:0000255; non-standard purine NTP pyrophosphatase; non-standard purine NTP pyrophosphatase {ECO:0000255; NTPase; NTPase {ECO:0000255; nucleoside triphosphate pyrophosphatase; nucleoside-triphosphate diphosphatase; nucleoside-triphosphate diphosphatase {ECO:0000255; Nucleoside-triphosphate pyrophosphatase; nucleoside-triphosphate pyrophosphatase {ECO:0000255; OK/SW-cl.9; Putative oncogene protein hlc14-06-p | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3704 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9BY32 | |
| ITPA | |
| Recombinant protein corresponding to Human ITPA | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only