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Tocris Bioscience™ J 147
Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels
215.00€ - 853.00€
Specifications
Purity | >99% |
---|---|
Product Type | J 147 |
Molecular Weight (g/mol) | 350.33 |
Inhibitors | J 147 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18793429
|
Tocris Bioscience™
5081/10 |
10 mg |
215.00€
10mg |
Estimated Shipment: 12-11-2024
Log in to see stock. |
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18769716
|
Tocris Bioscience™
5081/50 |
50 mg |
853.00€
50mg |
Estimated Shipment: 12-11-2024
Log in to see stock. |
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Description
Potent neuroprotective and neurotrophic compound. Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. Enhances memory in wild type rats. Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively. Orally active.Specifications
>99% | |
J 147 | |
350.33 | |
J 147 |
For Research Use Only