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Tocris Bioscience™ J 147

Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels

215.00€ - 853.00€

Specifications

Purity >99%
Product Type J 147
Molecular Weight (g/mol) 350.33
Inhibitors J 147
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18793429
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Tocris Bioscience™
5081/10
10 mg
215.00€
10mg
Estimated Shipment: 12-11-2024
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18769716
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Tocris Bioscience™
5081/50
50 mg
853.00€
50mg
Estimated Shipment: 12-11-2024
to see stock.
Add to basket
 
Description

Description

Potent neuroprotective and neurotrophic compound. Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. Enhances memory in wild type rats. Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively. Orally active.
Specifications

Specifications

>99%
J 147
350.33
J 147
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For Research Use Only