missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organic acids and derivatives
  6. Acrylic acids and derivatives
  7. JNJ 10191584 maleate, Tocris Bioscience™

JNJ 10191584 maleate, Tocris Bioscience™

Product Code. 18075572
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective H4 receptor antagonist; orally active

Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo.

Chemical Identifiers

CAS 869497-75-6
Molecular Formula C17H21ClN4O5
Molecular Weight (g/mol) 396.83
MDL Number MFCD09878266
InChI Key BODOIXYJOORQBQ-UHFFFAOYSA-N
Synonym jnj 10191584 maleate
PubChem CID 77519402
IUPAC Name 6-chloro-2-(4-methylpiperazine-1-carbonyl)-1H-1,3-benzodiazole; formic acid; prop-2-enoic acid
SMILES OC=O.OC(=O)C=C.CN1CCN(CC1)C(=O)C1=NC2=CC=C(Cl)C=C2N1

Specifications

Quantity 50 mg
Formula Weight 394.81
Percent Purity >99%
Chemical Name or Material JNJ 10191584 maleate
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.