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JZP 361, >99%, Tocris Bioscience™
Potent and selective reversible MAGL inhibitor
102.00€ - 383.00€
Specifications
Chemical Name or Material | [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- |
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CAS | 1680193-80-9 |
Purity Grade Notes | >99% |
Linear Formula | C22H20ClN5O |
Solubility Information | Soluble to 100mM in DMSO and to 20mM in ethanol |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
30000795
|
Tocris Bioscience
5851/10 |
10 mg |
102.00€
10mg |
Estimated Shipment: 29-01-2025
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30000842
|
Tocris Bioscience
5851/50 |
50 mg |
383.00€
50mg |
Estimated Shipment: 29-01-2025
Log in to see stock. |
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Description
Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.Specifications
[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- | |
>99% | |
Soluble to 100mM in DMSO and to 20mM in ethanol |
1680193-80-9 | |
C22H20ClN5O | |
405.88 |
Safety and Handling
Recommended Storage : Store at 4deg;C
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