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Lincomycin hydrochloride, Thermo Scientific Chemicals Product Code.: 15443869
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Lincomycin hydrochloride, Thermo Scientific Chemicals

Product Code. 15443869
5 g
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Quantity:
5 g
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Product Code. 15443869

Brand: Thermo Scientific Alfa Aesar J61251.06

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Description

Lincomycin hydrochloride, CAS # 859-18-7, is a compound showing antibacterial activity against a wide variety of bacteria, including Staphylococcal, Streptococcal, and Bacteroides fragilis infections. It also shows inhibitory activity against protein synthesis.

Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
  • Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA

Application

  • Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
  • It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
  • It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 859-18-7
Molecular Formula C18H35ClN2O6S
Molecular Weight (g/mol) 442.996
MDL Number MFCD00058237
InChI Key POUMFISTNHIPTI-OXVORJCQSA-N
PubChem CID 124080936
IUPAC Name (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochlorideShow MoreShow Less
SMILES CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl

Specifications

Type Lincomycin Hydrochloride
Physical Form Crystalline Powder
Color White
Quantity 5 g
Beilstein 4171650
Solubility Information Soluble in water
Formula Weight 443
Chemical Name or Material Lincomycin hydrochloride

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberX24K038 Certificate TypeCertificate of Analysis Date11/11/2024 Catalog NumberJ61251.03,J61251.14,J61251.06
Lot NumberW03K043 Certificate TypeCertificate of Analysis Date03/10/2024 Catalog NumberJ61251.03,J61251.14,J61251.06
Lot NumberP15K029 Certificate TypeCertificate of Analysis Date21/03/2024 Catalog NumberJ61251.03,J61251.14,J61251.06
Lot NumberX20J013 Certificate TypeCertificate of Analysis Date07/11/2023 Catalog NumberJ61251.03,J61251.14,J61251.06
Lot NumberS27J014 Certificate TypeCertificate of Analysis Date04/07/2023 Catalog NumberJ61251.03,J61251.14,J61251.06,J61251

Safety and Handling

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Product Identifier
  • Lincomycin hydrochloride
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
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RUO – Research Use Only

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