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LY 354740, Tocris Bioscience™

Product Code. 30001382
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Potent and highly selective group II mGlu agonist

Highly selective and potent agonist of group II mGlu receptors (EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors respectively and > 100000 nM at mGlu4, mGlu7, mGlu1a and mGlu5a receptors). Displays antianxiety and antiaddictive activity in vivo. Orally and systemically active.

Chemical Identifiers

CAS 176199-48-7
Molecular Formula C8H11NO4
Molecular Weight (g/mol) 185.18
MDL Number MFCD04113018
InChI Key VTAARTQTOOYTES-RGDLXGNYSA-N
Synonym eglumegad, eglumetad, 1s,2s,5r,6s-2-aminobicyclo 3.1.0 hexane-2,6-dicarboxylic acid, eglumegad inn, unii-onu5a67t2s, 3h eglumegad, chembl8759, onu5a67t2s, eglumegad usan
PubChem CID 213056
IUPAC Name (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
SMILES N[C@]1(CC[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O

Specifications

Quantity 10 mg
Formula Weight 185.18
Percent Purity >98%
Chemical Name or Material LY 354740
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