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  6. LY 379268, Tocris Bioscience™

LY 379268, Tocris Bioscience™

Product Code. 30001330
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Highly selective group II mGlu agonist

LY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active. LY379268 disodium salt also available.

Chemical Identifiers

CAS 191471-52-0
Molecular Formula C7H9NO5
Molecular Weight (g/mol) 187.151
InChI Key YASVRZWVUGJELU-MDASVERJSA-N
Synonym 1r,4r,5s,6r-4-amino-2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, d07grg, 4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1r,4r,5s,6r-4-amino-2-oxa-bicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 1s,2r,5r,6r-2-amino-4-oxabicyclo 3.1.0 hexane-2,6-dicarboxylic acid, 2-oxabicyclo 3.1.0 hexane-4,6-dicarboxylic acid, 4-amino-, 1r,4r,5s,6r-rel
PubChem CID 10197984
IUPAC Name (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
SMILES C1C(C2C(C2O1)C(=O)O)(C(=O)O)N

Specifications

Quantity 10 mg
Formula Weight 187.15
Percent Purity >99%
Chemical Name or Material LY 379268
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