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  8. MI 2 (MALT1 inhibitor), Tocris Bioscience™

MI 2 (MALT1 inhibitor), Tocris Bioscience™

Product Code. 30001668
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

MALT1 inhibitor

MALT1 inhibitor (IC50 = 5.84 μM). Binds directly to MALT1 and irreversibly suppresses protease function. Decreases NF-κB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo.

Chemical Identifiers

CAS 1047953-91-2
Molecular Formula C19H17Cl3N4O3
Molecular Weight (g/mol) 455.72
InChI Key TWJGQZBSEMDPQP-UHFFFAOYSA-N
Synonym mi 2 malt1 inhibitor, mi 2, 2-chloro-n-4-5-3,4-dichlorophenyl-3-2-methoxyethoxy-1h-1,2,4-triazol-1-yl phenyl acetamide, 2-chloro-n-4-5-3,4-dichlorophenyl-3-2-methoxyethoxy-1,2,4-triazol-1-yl phenyl acetamide, malt1 inhibitor mi-2, mi-2 malt1 inhibitor, mi 2 malt1 inhibitor; mi 2
PubChem CID 45942672
IUPAC Name 2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
SMILES COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl

Specifications

Quantity 50 mg
Formula Weight 455.72
Percent Purity >98%
Chemical Name or Material MI 2 (MALT1 inhibitor)
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