Learn More
N-Ethylmaleimide, 99+%, Thermo Scientific Chemicals
Description
N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+ dependent internucleosomal DNA fragmentation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
Specifications
Melting Point | 43°C to 46°C |
Boiling Point | 209°C to 211°C |
Flash Point | 73°C (163°F) |
Assay Percent Range | >99+% |
Quantity | 5 g |
Beilstein | 112448 |
Sensitivity | Light sensitive |
Solubility Information | Soluble in ethanol,water,chloroform,methanol and toluene. |
Formula Weight | 125.13 |
Physical Form | Crystalline |
Show More |
Safety and Handling
- N-Ethylmaleimide
- Danger
- Acute toxicity Category 2
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 B
- Skin sensitiser Category 1
- H300-Fatal if swallowed.
- H311-Toxic in contact with skin.
- H314-Causes severe skin burns and eye damage.
- H317-May cause an allergic skin reaction.
- H318-Causes serious eye damage.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Maleic acid N-ethylimide
RUO – Research Use Only