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  6. N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%, Thermo Scientific Chemicals

N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%, Thermo Scientific Chemicals

Product Code. 11444514
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Quantity:
5 g
25 g
100 g

Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 24589-78-4
Molecular Formula C6H12F3NOSi
Molecular Weight (g/mol) 199.25
MDL Number MFCD00000411
InChI Key MSPCIZMDDUQPGJ-UHFFFAOYSA-N
Synonym mstfa, n-methyl-n-trimethylsilyl trifluoroacetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl acetamide, n-methyl-n-trimethylsilyltrifluoroacetamide, acetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl, n-methyl-n-trimethylsilyl-trifluoroacetamide, acmc-209tfm
PubChem CID 32510
ChEBI CHEBI:85064
IUPAC Name 2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide
SMILES CN(C(=O)C(F)(F)F)[Si](C)(C)C

Specifications

Density 1.076
Boiling Point 130°C to 132°C
Flash Point 25°C (77°F)
Refractive Index 1.38
Quantity 25 g
UN Number UN1993
Beilstein 1941550
Sensitivity Moisture sensitive
Solubility Information Immiscible with water.
Formula Weight 199.25
Percent Purity 97%
Chemical Name or Material N-Methyl-N-(trimethylsilyl)trifluoroacetamide
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Safety and Handling

compliance-icons compliance-icons
Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 3
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H226-Flammable liquid and vapour.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
 Supplemental information
  • MIXTURE LIST-Contains : 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)-acetamide

RUO – Research Use Only

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