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NBI 35965 hydrochloride, Tocris Bioscience™

Name: NBI 35965 hydrochloride, Tocris Bioscience&trade;
Brand: Tocris Bioscience
Price: 233.00 EUR

Product Code. 18075422

10 mg

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Quantity:

10 mg

50 mg

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Product Code. 18075422

Brand: Tocris Bioscience 3100/10

233.00€ / 10mg

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This item is not returnable. View return policy

Description

Potent and selective CRF1 antagonist

Potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist (Ki values are 4 and > 10000 nM at CRF1 and CRF2 respectively). Inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro (pIC50 values are 7.1 and 6.9 respectively) and attenuates CRF and ACTH production in vivo. Orally active and brain penetrant with anxiolytic activity.

Specifications

Chemical Identifiers

CAS	603151-83-3
Molecular Formula	C21H23Cl3N4
Molecular Weight (g/mol)	437.793
InChI Key	LNYUWBPFYXPUIO-RSAXXLAASA-N
Synonym	nbi 35965 hydrochloride, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-4-methyl-7,8-dihydro-6h-1,3,6,8a-tetraazaacenaphthylene-hydrogen chloride 1/1, 7s-6-cyclopropylmethyl-2-2,4-dichlorophenyl-7-ethyl-7,8-dihydro-4-methyl-6h-1,3,6,8a-tetraazaacenaphthylene hydrochlorideShow More Show Less
PubChem CID	71433630
SMILES	CCC1CN2C3=C(C(=N2)C4=C(C=C(C=C4)Cl)Cl)N=C(C=C3N1CC5CC5)C.Cl

Specifications

Quantity	10 mg
Formula Weight	437.79
Percent Purity	>98%
Chemical Name or Material	NBI 35965 hydrochloride

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NBI 35965 hydrochloride, Tocris Bioscience™

Description

Specifications

Chemical Identifiers

Specifications

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