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Neomycin sulfate hydrate
CAS: 1405-10-3 | C23H48N6O17S | 712.72 g/mol
Brand: Thermo Scientific Alfa Aesar J61499.22
Quantity | 100 g |
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Description
Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsNeomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
Solubility
Soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Chemical Identifiers
1405-10-3 | |
712.72 | |
OIXVKQDWLFHVGR-DJUBFIBWNA-N | |
OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O |
C23H48N6O17S | |
MFCD29905465 | |
124080932 |
Specifications
Neomycin Sulfate | |
1405-10-3 | |
100 g | |
MFCD29905465 | |
Soluble in water | |
OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O | |
712.72 | |
908.87 (Anhydrous) |
Powder | |
White | |
C23H48N6O17S | |
14,6454 | |
OIXVKQDWLFHVGR-DJUBFIBWNA-N | |
(2S,3R,4S,5S,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3R,4S,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid | |
124080932 | |
Neomycin sulfate hydrate |
Safety and Handling
- Neomycin sulfate hydrate
Signal Word
- Danger
Hazard Category
- Reproductive toxicity Category 2
- Respiratory sensitiser Category 1
- Skin sensitiser Category 1
Hazard Statement
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H361d-Suspected of damaging the unborn child.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
Supplemental information
- MIXTURE LIST-Contains : Neomycin sulfate
Certificates
A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.
Lot Number | Certificate Type | Date | Catalog Number |
---|---|---|---|
P27L045 | Certificate of Analysis | 17/05/2025 | J61499.14,J61499.22 |
P03L022 | Certificate of Analysis | 05/03/2025 | J61499.14,J61499.22 |
S13K022 | Certificate of Analysis | 09/07/2024 | J61499.14,J61499.22 |
Q11K023 | Certificate of Analysis | 11/06/2024 | J61499.14,J61499.22 |
R26J010 | Certificate of Analysis | 07/06/2023 | J61499.22 |
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