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  6. NF 279, Tocris Bioscience™

NF 279, Tocris Bioscience™

Product Code. 18044362
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective P2X1 antagonist

NF 279 is a a potent and selective P2X1 antagonist (IC50 = 19 nM). Displays good selectivity over P2X2,(IC50 = 0.76 μM), P2X3 (IC50 = 1.62μM), P2X4 (IC50 > 300 μM), P2Y receptors and ecto-nucleotidases.

This product is supplied with a high degree of hydration and some residual NaCl, the amount of which are batch dependent. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Chemical Identifiers

CAS 202983-32-2
Molecular Formula C49H36N6Na6O23S6
Molecular Weight (g/mol) 1407.145
InChI Key RRKORSRLXJQAGK-UHFFFAOYSA-N
Synonym 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
PubChem CID 131850945
IUPAC Name sodium;8-[[4-[[4-[[4-[[4-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid
SMILES C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na]

Specifications

Quantity 10 mg
Formula Weight 1401.1
Percent Purity >98%
Chemical Name or Material NF 279
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