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Thermo Scientific Chemicals Paclitaxel, 99+% Product Code.: 10516261
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Thermo Scientific Chemicals Paclitaxel, 99+%

Product Code. 10516261
1 mg
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1 mg
5 mg
25 mg
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Product Code. 10516261

Brand: Thermo Scientific Chemicals 328420010

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59.30 EUR valid until 2025-12-31
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Description

Paclitaxel, also known as Taxol, CAS # 33069-62-4 is a chemotherapeutic drug that acts through stabilizing microtubule assembly and arresting cell cycle progression.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Paclitaxel is a naturally ocurring compound originally isolated from the tree T. brevifolia
  • Paclitaxel binds tubulin and stabilizes microtubule formation, preventing disassembly
  • Paclitaxel is used as a drug to arrest cells at the mitotic checkpoint and block cell cycle progression, thus inducing death of cancer cells

Applications

  • Paclitaxel can be used in preclinical laboratory research on diseases such as cancer, heart disease, inflammatory disorders, and hepatic fibrosis
  • Paclitaxel can be used as a tool in cell biology to study mitotic checkpoint arrest conditions and downstream signaling cascades
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 33069-62-4
Molecular Formula C47H51NO14
Molecular Weight (g/mol) 853.92
MDL Number MFCD00869953
InChI Key RCINICONZNJXQF-VAZQATRQSA-N
Synonym paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
PubChem CID 133640187
IUPAC Name (1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoateShow MoreShow Less
SMILES CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1Show MoreShow Less

Specifications

Melting Point 213.0°C to 216.0°C
Color White
Infrared Spectrum Authentic
Assay Percent Range 99% min. (HPLC)
Quantity 1 mg
Merck Index 15, 7081
Solubility Information Solubility in water: sparingly soluble. Other solubilities: soluble in methanol,dmso,acetonitrile
Formula Weight 853.9
Percent Purity 99+%
Physical Form Powder
Chemical Name or Material Paclitaxel, 99+%
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberA0462182 Certificate TypeCertificate of Analysis Date05/06/2024 Catalog Number328420250,328420010,328420050
Lot NumberA0457731 Certificate TypeCertificate of Analysis Date10/11/2023 Catalog NumberC22322.30
Lot NumberA0457732 Certificate TypeCertificate of Analysis Date10/11/2023 Catalog Number328420010,328420050,328420250
Lot NumberA0451334 Certificate TypeCertificate of Analysis Date02/05/2023 Catalog NumberC22322.30
Lot NumberA0450098 Certificate TypeCertificate of Analysis Date02/05/2023 Catalog Number328420250,328420010,328420050

Safety and Handling

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Product Identifier
  • Paclitaxel
 Signal Word
  • Danger
 Hazard Category
  • LONG-TERM AQUATIC HAZARD Chronic 4
  • Serious eye damage/eye irritation Category 1
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H318-Causes serious eye damage.
  • H335-May cause respiratory irritation.
  • H361-Suspected of damaging fertility or the unborn child.
  • H413-May cause long lasting harmful effects to aquatic life.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
SDS

RUO – Research Use Only

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