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PHCCC, Tocris Bioscience™

Product Code. 30001163
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent group I mGlu antagonist

Group I metabotropic glutamate receptor antagonist (IC50 ∽ 3 μM); 67 times more potent than (S)-4-carboxyphenylglycine (Cat. No. 0323). Also a positive allosteric modulator for mGlu4a; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro. Displays antiParkinsonian effects in rats in vivo.

Chemical Identifiers

CAS 177610-87-6
Molecular Formula C17H14N2O3
Molecular Weight (g/mol) 294.31
InChI Key FPXPIEZPAXSELW-CYVLTUHYSA-N
Synonym phccc, -phccc, d0h6bg, 7e-7-hydroxyimino-n-phenyl-1,7a-dihydrocyclopropa b chromene-1a-carboxamide, e-7-hydroxyimino-n-phenyl-1,1a,7,7a-tetrahydrocyclopropa b chromene-1a-carboxamide, 6z-6-hydroxyimino-n-phenyl-2-oxatricyclo 5.4.0.0 3 ,? undeca-1 11 ,7,9-triene-3-carboxamide
PubChem CID 5866327
IUPAC Name (7E)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide
SMILES C1C2C1(OC3=CC=CC=C3C2=NO)C(=O)NC4=CC=CC=C4

Specifications

Quantity 10 mg
Formula Weight 294.31
Percent Purity >98%
Chemical Name or Material PHCCC
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