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Phenamil, Tocris Bioscience™

Product Code. 30001501
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Quantity:
10 mg
50 mg
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Description

Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels

TRPP3 channel inhibitor (IC50 = 0.14 μM). Also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Derivative of amiloride (Cat. No. 0890).

Chemical Identifiers

CAS 1161-94-0
Molecular Formula C13H16ClN7O4S
Molecular Weight (g/mol) 401.826
InChI Key MHPIZTURFVSLTJ-UHFFFAOYSA-N
Synonym phenamil methanesulfonate, phenamil methanesulfonate salt, 3,5-diamino-6-chloro-n-imino phenylamino methyl pyrazinecarboxamide methanesulfonate salt, lopac-p-203, phenamil methanesulfonate salt, solid, phenamil methanesulfonate free base, 3,5-diamino-6-chloro-n-n-phenylcarbamimidoyl pyrazine-2-carboxamide methanesulfonate, 3,5-diamino-6-chloro-n-imino phenylamino methyl-pyrazinecarboxamide methansulfonate
PubChem CID 9604979
IUPAC Name 3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;methanesulfonic acid
SMILES CS(=O)(=O)O.C1=CC=C(C=C1)NC(=NC(=O)C2=C(N=C(C(=N2)Cl)N)N)N

Specifications

Quantity 50 mg
Formula Weight 401.83
Percent Purity >99%
Chemical Name or Material Phenamil
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